Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses
نویسندگان
چکیده
منابع مشابه
SARS-COV-2 Virus; Immune Responses and The Immunopathogenesis
Abstract Background and Objectives Clinical features of SARS-COV-2 virus include fever, headache, cough, sore throat, and shortness of breath, and in severe forms it leads to disseminated intravascular coagulation, septic shock, and ultimately death. Excessive secretion of proinflammatory cytokines such as TNF-α, IL-6, and IL-1 leads to cytokine storms in this disease. The emergence of new va...
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ژورنال
عنوان ژورنال: Immunity
سال: 2020
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2020.11.015